⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458050 | 1.00 | — | — | |
| SCHEMBL14388431 | 1.00 | — | — | |
| SCHEMBL8186028 | 1.00 | — | — | |
| SCHEMBL8186027 | 1.00 | — | — | |
| SCHEMBL458049 | 1.00 | — | — | |
| SCHEMBL13406449 | 1.00 | — | — | |
| SCHEMBL15703578 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL74585 | 0.98 | GRIK1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL712566 | 0.98 | GRIK1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL713389 | 0.98 | GRIK1 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | claimed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| EP-4725952-A1 | COMPOUNDS COMPRISING NON-CANONICAL AMINO ACIDS AND USES THEREOF | ETH Zurich (CH) | 2026-04-15 | — | — | EP | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| WO-2023084124-A1 | NOVEL BETA-LACTONE INHIBITORS OF HYDROLYTIC ENZYMES AND THEIR MEDICAL AND NON MEDICAL USES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-19 | — | — | WO | disclosed |
| EP-4180035-A1 | NOVEL BETA-LACTONE INHIBITORS OF HYDROLYTIC ENZYMES AND THEIR MEDICAL AND NON MEDICAL USES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-17 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| CN-114540446-A | High-yield culture medium for producing bleomycin E by using deep sea streptomycete gene engineering mutant strain and large-scale fermentation process thereof | 华东理工大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-111303247-B | Marine cyclopeptide compound and application thereof in preparation of mycobacterium tuberculosis resistant medicines | 中国科学院南海海洋研究所 | 2022-03-22 | — | — | CN | disclosed |
| EP-0787010-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996020949-A1 | PEPTIDE AND PEPTIDE ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | disclosed |
| WO-1996012499-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| WO-1995003321-A1 | METHOD FOR ENDOMODIFICATION OF PROTEINS | BIONEBRASKA, INC. (US) | 1995-02-02 | — | — | WO | disclosed |
| US-5279954-A | Coupling a nucleophile to protein; binding to other adjuvants | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA AND BIONEBRASKA (US) | 1994-01-18 | — | — | US | disclosed |
| US-5234820-A | Coupling nucleophile to protein, binding to auxiliary substance | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0479897-A1 | ENZYMATICALLY BINDING BIOACTIVE MATERIALS TO PROTEINS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000296-A1 | ENZYMATICALLY BINDING BIOACTIVE MATERIALS TO PROTEINS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0308983-A2 | NMR imaging with Mn(II) coordination compositions | SALUTAR, INC. (US) | 1989-03-29 | — | — | EP | disclosed |