⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458050 | 1.00 | — | — | |
| SCHEMBL14388431 | 1.00 | — | — | |
| SCHEMBL866068 | 1.00 | — | — | |
| SCHEMBL8186028 | 1.00 | — | — | |
| SCHEMBL458049 | 1.00 | — | — | |
| SCHEMBL13406449 | 1.00 | — | — | |
| SCHEMBL15703578 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL74585 | 0.98 | GRIK1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL712566 | 0.98 | GRIK1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL713389 | 0.98 | GRIK1 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | disclosed |
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | disclosed |
| US-8748570-B2 | Insulin analogues | SYNGENE LIMITED (AU) | 2014-06-10 | — | — | US | disclosed |
| US-8748570-B2 | Insulin analogues | SYNGENE LIMITED (AU) | 2014-06-10 | — | — | US | disclosed |
| US-20120225811-A1 | INSULIN ANALOGUES | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2012-09-06 | — | — | US | disclosed |
| US-20120225811-A1 | INSULIN ANALOGUES | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2012-09-06 | — | — | US | disclosed |
| WO-2011146972-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011146974-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011146973-A1 | INSULIN ANALOGUES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| US-6015879-A | COMPOUNDS FOR TREATMENT OF NERVOUS SYSTEM DISORDERS INCLUDING ALZHEIMER'S DISEASE, COGNITION DEFECTS, DOWN'S SYNDROME, PARKINSON'S DISEASE, CEREBRAL HEMORRHAGE WITH AMYLOIDOSIS, DEMENTIA PUGILISTICA, AND HEAD TRAUMA | SIBIA NEUROSCIENCES, INC. (US) | 2000-01-18 | — | — | US | disclosed |
| US-5969100-A | Peptide, peptide analog and amino acid analog protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| US-5962419-A | NERVOUS SYSTEM DISORDERS; BRAIN DISORDERS | SIBIA NEUROSCIENCES, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| US-5872101-A | Methods of treating neurodegenerative disorders using protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5863902-A | Methods of treating neurodegenerative disorders using protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| US-5804560-A | MODULATES PROCESSING OF AMYLOID PRECURSOR PROTEIN | SIBIA NEUROSCIENCES, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5714471-A | USEFUL IN INDICATING NEURODEGENERATIVE DISORDERS CHARACTERIZED BY DEPOSITION OF CEREBRAL AMYLOID | SIBIA NEUROSCIENCES, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0800528-A1 | PEPTIDE AND PEPTIDE ANALOG PROTEASE INHIBITORS | Sibia Neurosciences, Inc. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020725-A2 | PEPTIDE, PEPTIDE ANALOG AND AMINO ACID ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | disclosed |
| WO-1996020949-A1 | PEPTIDE AND PEPTIDE ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | disclosed |