SCHEMBL4580674

SCHEMBL4580674

CC(C)(c1ccccc1)c1ccc(N)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ESR2 Q92731 4/20 0.60
CYP3A4 P08684 4/20 0.60
ALDH1A1 P00352 3/20 0.60
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 2/20 0.48
NR3C2 P08235 3/20 0.47
TAAR1 Q96RJ0 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 3/20 0.45
HPGD P15428 2/20 0.45
MAPK1 P28482 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
AR P10275 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL20955931 0.95 TSHR (0.55) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL25286965 0.93 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL108051 0.89 CYP3A4 (0.52) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL1729158 0.89 CYP3A4 (0.52) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL126726 0.89 CYP3A4 (0.52) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL1501485 0.88 ALDH1A1 (0.66) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL822627 0.88 ALDH1A1 (0.63) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL14302764 0.88 CYP3A4 (0.54) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL822632 0.88 ALDH1A1 (0.63) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL8641636 0.87 ALDH1A1 (0.50) ESR1ESR2CYP3A4ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368244-A Synthetic method of 2-aryl-2- (4-aminophenyl) propane 北京鼎材科技有限公司 2022-11-22 CN claimed
CN-113671068-A Method for analyzing environmental pollutant targeting exposure component in blood plasma and application thereof 暨南大学 2021-11-19 CN claimed
CN-112986416-A Multi-component large-flux detection method for plastic additive in atmospheric particulates 暨南大学 2021-06-18 CN claimed
CN-112469776-A Composition comprising a metal oxide and a metal oxide 瑞士新集团有限公司 2021-03-09 CN claimed
CN-109970975-A A kind of high voltage holding ratio type polyimides and its preparation method and application 北京波米科技有限公司 2019-07-05 CN claimed
CN-104221176-B Thermooxidatively stable, pendant polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and components thereof 住友电木株式会社 2017-03-01 CN claimed
US-5731125-A FOR FORMING RESIST FILM JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-03-24 US claimed
EP-0166321-B1 HYDROPHOBIC POLYAMIDES BAYER AG (DE) 1990-08-08 EP claimed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US claimed
CN-115368244-B Synthesis method of 2-aryl-2- (4-aminophenyl) propane 北京鼎材科技有限公司 2025-08-08 CN disclosed
US-20250214294-A1 ULTRAHIGH TEMPERATURE, LOW SCORCH METHOD OF MAKING CROSSLINKABLE COMPOUND COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-03 US disclosed
WO-2025132945-A1 LUBRICANT COMPOSITIONS CONTAINING ARALKYL SUBSTITUTED DIPHENYLAMINE ANTIOXIDANT INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-26 WO disclosed
EP-4532161-A1 ULTRAHIGH TEMPERATURE, LOW SCORCH METHOD OF MAKING CROSSLINKABLE COMPOUND COMPOSITIONS Dow Global Technologies LLC (US) 2025-04-09 EP disclosed
CN-119325419-A Ultra-high temperature, low scorch process for preparing crosslinkable compound compositions 陶氏环球技术有限责任公司 2025-01-17 CN disclosed
EP-0166321-A2 Hydrophobic polyamides BAYER AG (DE) 1986-01-02 EP disclosed
EP-0069065-B1 PROCESS FOR THE ALKYLATION OR ARALKYLATION OF AROMATIC AMINES CIBA-GEIGY AG (CH) 1985-02-13 EP disclosed
US-4436936-A ACID CATALYSTS CIBA-GEIGY CORPORATION (US) 1984-03-13 US disclosed
EP-0069065-A1 Process for the alkylation or aralkylation of aromatic amines CIBA-GEIGY AG (CH) 1983-01-05 EP disclosed
US-4247456-A Water-insoluble monoazo pyridone dye CASSELLA AKTIENGESELLSCHAFT (DE) 1981-01-27 US disclosed
US-3957749-A WATER-INSOLUBLE MONOAZO PYRIDINE DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed