Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822627 | 1.00 | ALDH1A1 (0.63) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL5424442 | 0.90 | ESR1 (0.58) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL1591676 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL4580674 | 0.88 | ESR1 (0.60) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL12153728 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL13049481 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL17988507 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL12128820 | 0.85 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL12337352 | 0.85 | ALDH1A1 (0.69) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 | |
| SCHEMBL13700827 | 0.84 | ESR1 (0.52) | ALDH1A1CYP3A4TDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492508-B2 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-07-23 | — | — | US | disclosed |
| US-8492508-B2 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-07-23 | — | — | US | disclosed |
| US-8367797-B2 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-02-05 | — | — | US | disclosed |
| US-8367797-B2 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-02-05 | — | — | US | disclosed |
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NOS2, NOS1, NOS3 | ALDH1A1 2358/4885CYP3A4 1179/4885TDP1 1336/4885 |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | THEM6, NOS2, NOS1 | ALDH1A1 2644/4885CYP3A4 1102/4885TDP1 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.