Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL839513 | 0.91 | CA4 (0.52) | CA1CA4GPR84CA2FFAR3 | |
| SCHEMBL1614090 | 0.86 | CA4 (0.56) | CA1CA4GPR84CA2FFAR3 | |
| Potassium Ion SCHEMBL29060945 | 0.86 | CA4 (0.52) | CA1CA4GPR84CA2FFAR3 | |
| SCHEMBL29686680 | 0.86 | CA4 (0.56) | CA1CA4GPR84CA2FFAR3 | |
| Silver SCHEMBL6743355 | 0.86 | CA4 (0.52) | CA1CA4GPR84CA2FFAR3 | |
| SCHEMBL6743367 | 0.86 | CA4 (0.52) | CA1CA4GPR84CA2FFAR3 | |
| SCHEMBL29566757 | 0.86 | CA4 (0.56) | CA1CA4GPR84CA2FFAR3 | |
| Zinc Ion SCHEMBL30953896 | 0.77 | NFKB1 (0.56) | CA1CA4GPR84CA2FFAR3 | |
| Valeric Acid SCHEMBL29627993 | 0.74 | CA1 (0.65) | CA1CA4GPR84CA2FFAR3 | |
| Malic Acid SCHEMBL27944022 | 0.73 | CA4 (0.81) | CA1CA4CA2FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906415-B2 | Device having zinc oxide semiconductor and indium/zinc electrode | XEROX CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080023698-A1 | Device having zinc oxide semiconductor and indium/zinc electrode | XEROX CORPORATION | 2008-01-31 | — | — | US | disclosed |
| US-20070287221-A1 | Fabrication process for crystalline zinc oxide semiconductor layer | XEROX CORPORATION | 2007-12-13 | — | — | US | disclosed |