SCHEMBL4580893

SCHEMBL4580893

O=S(=O)(c1ccc(Cl)cc1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

nearest known ligand 0.81

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.81
L3MBTL1 Q9Y468 3/20 0.76
KMT2A Q03164 3/20 0.75
MAPT P10636 1/20 0.75
MEN1 O00255 2/20 0.73
HTT P42858 1/20 0.73
LMNA P02545 2/20 0.70
SMN1; SMN2 Q16637 2/20 0.69
POLB P06746 2/20 0.67
ALDH1A1 P00352 2/20 0.67
MAPK1 P28482 1/20 0.67
PKM P14618 2/20 0.65
CNR1 P21554 1/20 0.65
PKLR P30613 1/20 0.65
USP2 O75604 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10355428 1.00 ATM (0.81) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL2705461 0.91 L3MBTL1 (0.83) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5251954 0.91 L3MBTL1 (0.77) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5249795 0.90 L3MBTL1 (0.86) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5251337 0.90 L3MBTL1 (0.86) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5250380 0.89 HSD11B1 (0.78) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5915296 0.88 KMT2A (0.66) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5307467 0.86 POLB (0.73) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL654548 0.86 MAPT (1.00) ATML3MBTL1KMT2AMAPTMEN1
SCHEMBL5306092 0.86 MAPT (0.69) ATML3MBTL1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
US-20080312349-A1 METHOD OF MAKING AND USING MEMBRANE GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
US-20080203012-A1 MEMBRANE, APPARATUS, AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
US-20080207822-A1 COMPOSITION AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed