Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389204 | 0.77 | HTR2A (0.35) | HTR2AHRH1RETHTR2CKDM1A | |
| SCHEMBL4307808 | 0.75 | HTR2A (0.34) | HTR2AHRH1RETHTR2CGRIN2D | |
| SCHEMBL6521360 | 0.75 | HTR2A (0.35) | HTR2AHRH1HTR2COPRM1 | |
| SCHEMBL458123 | 0.75 | HTR2A (0.34) | HTR2AHRH1RETHTR2CGRIN2D | |
| SCHEMBL458495 | 0.75 | HTR2A (0.35) | HTR2AHRH1HTR2COPRM1 | |
| SCHEMBL874497 | 0.75 | HTR2A (0.34) | HTR2AHRH1RETHTR2CGRIN2D | |
| SCHEMBL4290508 | 0.75 | HTR2A (0.35) | HTR2AHRH1HTR2COPRM1 | |
| SCHEMBL8418267 | 0.75 | KDM1A (0.39) | HTR2AHTR2CKDM1A | |
| SCHEMBL3634708 | 0.72 | PRCP (0.38) | HTR2AHTR2C | |
| SCHEMBL8890669 | 0.72 | CHRNB2 (0.33) | HTR2AKDM1AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841433-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| WO-2013162077-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-31 | — | — | WO | disclosed |
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| EP-2310378-A2 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010019772-A2 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2006065809-A2 | HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| EP-1157003-A1 | ACYLATED AMINOACETONITRILES AS CYSTEINE PROTEASE INHIBITORS | AstraZeneca AB (SE) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000048992-A1 | ACYLATED AMINOACETONITRILES AS CYSTEINE PROTEASE INHIBITORS | ASTRAZENECA AB (SE) | 2000-08-24 | — | — | WO | disclosed |
| WO-1997040010-A1 | HALOGENATED NAPHTHYL METHOXY PIPERIDINES FOR MAPPING SEROTONIN TRANSPORTER SITES | EMORY UNIVERSITY (US) | 1997-10-30 | — | — | WO | disclosed |
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |