⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15063986 | 0.82 | ESR2 (0.48) | — | |
| SCHEMBL105204 | 0.75 | CA1 (0.48) | — | |
| SCHEMBL1067320 | 0.75 | DRD1 (0.37) | — | |
| SCHEMBL2325392 | 0.75 | KIF11 (0.33) | — | |
| SCHEMBL2970309 | 0.75 | NQO1 (0.54) | — | |
| SCHEMBL19435886 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL1029610 | 0.73 | — | — | |
| SCHEMBL5168543 | 0.73 | — | — | |
| SCHEMBL1964190 | 0.73 | — | — | |
| SCHEMBL8267 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | claimed |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-31 | — | — | US | claimed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | claimed |
| CN-105968115-B | Quinolines, preparation method, intermediate, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2018-11-09 | — | — | CN | claimed |
| CN-105531265-B | Pesticidal compounds | 巴斯夫欧洲公司 | 2018-07-20 | — | — | CN | claimed |
| US-20180118718-A1 | Substituted Quinoxaline Derivatives | SELVITA S.A. (PL) | 2018-05-03 | — | — | US | claimed |
| EP-3294728-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-03-21 | — | — | EP | claimed |
| CN-107312009-A | Quinolines, its preparation method, intermediate, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2017-11-03 | — | — | CN | claimed |
| EP-3022185-B1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2017-09-06 | — | — | EP | claimed |
| CN-104109166-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2017-06-20 | — | — | CN | claimed |
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | claimed |
| US-6780996-B2 | KINASE INHIBITORS; ANTICANCER AGENTS | WYETH HOLDINGS CORPORATION | 2004-08-24 | — | — | US | claimed |
| EP-0463488-B2 | O-Benzyl oxime ethers and fungicides containing them | BASF AG (DE) | 2004-04-21 | — | — | EP | claimed |
| US-20030212276-A1 | Process for the preparation of 7-substituted-3 quinolinecarbonitriles | WYETH HOLDINGS CORPORATION | 2003-11-13 | — | — | US | claimed |
| WO-2003093241-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH HOLDINGS CORPORATION (US) | 2003-11-13 | — | — | WO | claimed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | claimed |
| EP-0969829-A4 | SYNTHETIC TECHNIQUES AND INTERMEDIATES FOR POLYHYDROXY, DIENYLLACTONES AND MIMICS THEREOF | UNIV PENNSYLVANIA (US) | 2002-06-12 | — | — | EP | claimed |
| EP-0969829-A1 | SYNTHETIC TECHNIQUES AND INTERMEDIATES FOR POLYHYDROXY, DIENYLLACTONES AND MIMICS THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1998024429-A1 | SYNTHETIC TECHNIQUES AND INTERMEDIATES FOR POLYHYDROXY, DIENYLLACTONES AND MIMICS THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-06-11 | — | — | WO | claimed |
| US-5602174-A | TREATMENT OR PROPHYLAXIS OF ANGINA | BEECHAM WUEFLING GMBH & CO. (DE) | 1997-02-11 | — | — | US | claimed |