Methacrylic Acid

Methacrylic Acid

SCHEMBL4581267

C=C(C)C(=O)O.C=C(C)C(=O)OCC.C=C(C)C(=O)OCC(C)C

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.75
THRB P10828 1/20 0.46
ALDH1A1 P00352 8/20 0.39
GPR35 Q9HC97 1/20 0.37
MAPT P10636 1/20 0.37
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 1/20 0.36
GLO1 Q04760 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6560644 0.94 TSHR (0.84) TSHRTHRBALDH1A1GPR35MAPT
Methacrylic Acid SCHEMBL1472434 0.93 TSHR (0.88) TSHRTHRBALDH1A1SMN1; SMN2
SCHEMBL9645536 0.89 TSHR (0.75) TSHRTHRBALDH1A1GPR35MAPT
Acrylic Acid SCHEMBL5959113 0.88 TSHR (0.68) TSHRTHRBALDH1A1GPR35MAPT
SCHEMBL24562 0.87 TSHR (1.00) TSHRTHRBALDH1A1SMN1; SMN2
Methacrylic Acid SCHEMBL9472725 0.87 THRB (0.57) TSHRTHRBALDH1A1MAPTCYP2D6
Methacrylic Acid SCHEMBL974640 0.87 THRB (0.57) TSHRTHRBALDH1A1MAPTCYP2D6
Methacrylic Acid SCHEMBL2802555 0.87 THRB (0.57) TSHRTHRBALDH1A1MAPTCYP2D6
Ether SCHEMBL4279341 0.85 TSHR (0.81) TSHRTHRBALDH1A1GPR35CYP2D6
Methacrylic Acid SCHEMBL29065401 0.85 THRB (0.55) TSHRTHRBALDH1A1MAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829703-B1 Infrared sensitive planographic printing plate precursor FUJIFILM CORP (JP) 2008-09-17 EP disclosed
US-7381518-B2 Suppport coated with recording layer composed of a water-insoluble and alkali-soluble resin and an infrared absorbent, and with an organic polymer on the other side, which is coated using a solvent; total amount of solvent remaining in the polymer layer is 10 mg per gram of the polymer or less. FUJIFILM CORPORATION (JP) 2008-06-03 US disclosed
US-7306891-B2 Recording layer containing a water-insoluble and alkali-soluble resin and an infrared absorbent, and an organic polymer layer with an arithmetic mean roughness Ra of 0.05 to 0.40 mu m on a face of the plate opposite to the recording layer; long-chain alkyl group-containing polymer matting agent FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
EP-1829703-A1 Infrared sensitive planographic printing plate precursor FUJIFILM Corporation (JP) 2007-09-05 EP disclosed
US-20070077518-A1 Recording layer containing a water-insoluble and alkali-soluble resin and an infrared absorbent, and an organic polymer layer with an arithmetic mean roughness Ra of 0.05 to 0.40 mu m on a face of the plate opposite to the recording layer; long-chain alkyl group-containing polymer matting agent FUJI PHOTO FILM CO., LTD. 2007-04-05 US disclosed
EP-1759837-A2 Infrared-sensitive planographic printing plate precursor Fuji Photo Film Co., Ltd. (JP) 2007-03-07 EP disclosed
US-20070048661-A1 Suppport coated with recording layer composed of a water-insoluble and alkali-soluble resin and an infrared absorbent, and with an organic polymer on the other side, which is coated using a solvent; total amount of solvent remaining in the polymer layer is 10 mg per gram of the polymer or less. FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed