SCHEMBL4581300

SCHEMBL4581300

O=C(Cc1ccccc1)OCC(COC(=O)Cc1ccccc1)OC(=O)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
ALDH1A1 P00352 2/20 0.59
MAPK1 P28482 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PAM P19021 1/20 0.58
ADRB2 P07550 1/20 0.52
ADRB1 P08588 1/20 0.52
ADRB3 P13945 1/20 0.52
PRKCA P17252 1/20 0.49
PRKCD Q05655 1/20 0.49
KMT2A Q03164 1/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
AKR1B1 P15121 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
MGLL Q99685 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10087950 0.88 TSHR (0.53) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL6898542 0.88 TSHR (0.56) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL13397998 0.83 TSHR (0.67) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL9463746 0.81 ADRB2 (0.68) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL3276203 0.81 TSHR (0.56) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL28043002 0.81 TSHR (0.51) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL769363 0.80 TSHR (0.62) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL28312880 0.80 TSHR (0.68) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL9464170 0.79 ALDH1A1 (0.51) TSHRALDH1A1MAPK1L3MBTL1PAM
SCHEMBL9464184 0.78 ALDH1A1 (0.50) TSHRALDH1A1MAPK1L3MBTL1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed