Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581336 | 0.84 | ALDH1A1 (0.43) | CYP3A4LMNACYP2D6MAPK1GAA | |
| Tetramethylammonium Ion SCHEMBL216795 | 0.80 | GAA (0.56) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL4463639 | 0.80 | GAA (0.56) | CYP3A4LMNAGAAALDH1A1CYP2C9 | |
| SCHEMBL8505186 | 0.79 | LMNA (0.55) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL23754813 | 0.79 | LMNA (0.58) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL193325 | 0.78 | GAA (0.45) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL29195216 | 0.78 | GAA (0.50) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL11656541 | 0.77 | CA1 (0.54) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL3363602 | 0.76 | GAA (0.43) | CYP3A4LMNACYP2D6MAPK1THPO | |
| SCHEMBL19812378 | 0.76 | LMNA (0.43) | CYP3A4LMNACYP2D6MAPK1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101405893-A | Optoelectronic device with improved efficiency | GEN ELECTRIC (US) | 2009-04-08 | — | — | CN | claimed |
| EP-1999804-A2 | OPTO-ELECTRONIC DEVICES EXHIBITING ENHANCED EFFICIENCY | GENERAL ELECTRIC COMPANY (US) | 2008-12-10 | — | — | EP | claimed |
| WO-2007111763-A2 | OPTO-ELECTRONIC DEVICES EXHIBITING ENHANCED EFFICIENCY | GENERAL ELECTRIC COMPANY (US) | 2007-10-04 | — | — | WO | claimed |
| US-20070215879-A1 | Opto-electronic devices exhibiting enhanced efficiency | GENERAL ELECTRIC COMPANY (US) | 2007-09-20 | — | — | US | claimed |
| CN-101405893-A | Optoelectronic device with improved efficiency | GEN ELECTRIC (US) | 2009-04-08 | — | — | CN | disclosed |
| EP-1999804-A2 | OPTO-ELECTRONIC DEVICES EXHIBITING ENHANCED EFFICIENCY | GENERAL ELECTRIC COMPANY (US) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007111763-A2 | OPTO-ELECTRONIC DEVICES EXHIBITING ENHANCED EFFICIENCY | GENERAL ELECTRIC COMPANY (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070215879-A1 | Opto-electronic devices exhibiting enhanced efficiency | GENERAL ELECTRIC COMPANY (US) | 2007-09-20 | — | — | US | disclosed |