Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 6/20 | 0.38 |
| ▸ | Q9HBH1 | 3/20 | 0.38 | |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581335 | 1.00 | BMP1 (0.38) | BMP1PDFMMP12 | |
| SCHEMBL4581327 | 1.00 | BMP1 (0.38) | BMP1PDFMMP12 | |
| SCHEMBL3900866 | 0.76 | CA2 (0.50) | BMP1 | |
| SCHEMBL3902711 | 0.76 | CA2 (0.50) | BMP1 | |
| SCHEMBL1597464 | 0.75 | BMP1 (0.43) | BMP1PDFMMP12 | |
| SCHEMBL1597465 | 0.75 | BMP1 (0.43) | BMP1PDFMMP12 | |
| SCHEMBL1597461 | 0.75 | BMP1 (0.43) | BMP1PDFMMP12 | |
| SCHEMBL4318257 | 0.74 | GRIK1 (0.49) | BMP1 | |
| SCHEMBL6023663 | 0.73 | BMP1 (0.37) | BMP1PDFMMP12 | |
| SCHEMBL6025846 | 0.73 | BMP1 (0.37) | BMP1PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |