⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102447 | 0.81 | — | — | |
| SCHEMBL58209 | 0.79 | — | — | |
| SCHEMBL158133 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL29140292 | 0.77 | — | — | |
| SCHEMBL27702959 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL28325875 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL27822839 | 0.71 | GAA (0.31) | — | |
| SCHEMBL2035545 | 0.70 | ALDH1A1 (0.30) | — | |
| SCHEMBL458035 | 0.70 | — | — | |
| SCHEMBL3693116 | 0.70 | CA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-11926758-B2 | Polytriazole coating materials for metal substrates | SAUDI ARABIAN OIL COMPANY (SA) | 2024-03-12 | — | — | US | claimed |
| US-11814473-B2 | Polytriazole copolymer compositions | SAUDI ARABIAN OIL COMPANY (SA) | 2023-11-14 | — | — | US | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| CN-116217457-A | 4-amino-1H-pyrrole compound, preparation method and application | 中国药科大学 | 2023-06-06 | — | — | CN | claimed |
| CN-111848412-B | Method for efficiently realizing N-alkylation reaction by using cycloiridium catalyst | 赣南医学院 | 2023-05-12 | — | — | CN | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| US-20220017688-A1 | POLYTRIAZOLE COPOLYMER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2022-01-20 | — | — | US | claimed |
| US-20220017774-A1 | POLYTRIAZOLE COATING MATERIALS FOR METAL SUBSTRATES | SAUDI ARABIAN OIL COMPANY (SA) | 2022-01-20 | — | — | US | claimed |
| CN-110642918-B | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| US-20020193608-A1 | Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds | ELABDELLAOUI HASSAN M (US) | 2002-12-19 | — | — | US | claimed |
| WO-2002090346-A1 | PHTHALAZINE DERIVATIVES WITH ANGIOGENESIS INHIBITING ACTIVITY | NOVARTIS AG (CH) | 2002-11-14 | — | — | WO | claimed |
| CN-1367695-A | Phthalazine derivatives for the treatment of inflammatory diseases | NOVARTIS AG (CH) | 2002-09-04 | — | — | CN | claimed |
| US-6380210-B1 | USEFUL IN DIAGNOSIS AND TREATMENT OF ANXIETY, DOWN SYNDROME, SLEEP, COGNITIVE AND SEIZURE DISORDERS, DEPRESSION, OVERDOSE WITH BENZODIAZEPINE DRUGS, AND ENHANCEMENT OF MEMORY AND ALERTNESS | NEUROGEN CORPORATION | 2002-04-30 | — | — | US | claimed |
| US-6359144-B1 | BIOSYNTHESIS; SCREENING | LION BIOSCIENCE AG (DE) | 2002-03-19 | — | — | US | claimed |
| EP-1165085-A1 | PHTHALAZINE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | Novartis AG (CH) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059509-A1 | PHTHALAZINE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | NOVARTIS AG (CH) | 2000-10-12 | — | — | WO | claimed |
| US-5856107-A | Combinatorial libraries of imidazol-pyrido-indole and imidazol-pyrido-benzothiophene derivatives, methods of making the libraries and compounds therein | TREGA BIOSCIENCES, INC. (US) | 1999-01-05 | — | — | US | claimed |
| WO-1998034113-A1 | COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| WO-1998034112-A1 | COMBINATORIAL LIBRARIES OF IMIDAZOL-PYRIDO-INDOLES AND IMIDAZOL-PYRIDO-BENZOTHIOPHENE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |