SCHEMBL4581948

SCHEMBL4581948

NC(=O)c1ccc2c(c1)C1(c3ccccc3-2)c2ccccc2-c2ccc(C(N)=O)cc21

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 14/20 0.65
L3MBTL1 Q9Y468 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
HTR7 P34969 2/20 0.42
HTR2B P41595 2/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134285 0.85 PDK2 (0.58) PDK2L3MBTL1TDP1
SCHEMBL29114 0.85 PDK2 (0.58) PDK2L3MBTL1TDP1
SCHEMBL15041018 0.85 PDK2 (0.47) PDK2TDP1
SCHEMBL134286 0.85 PDK2 (0.58) PDK2L3MBTL1TDP1
SCHEMBL2456262 0.84 PDK2 (0.55) PDK2KMT2APOLBTDP1
SCHEMBL12337045 0.84 PDK2 (0.60) PDK2L3MBTL1TDP1
SCHEMBL31146728 0.84 PDK2 (0.55) PDK2KMT2APOLBTDP1
SCHEMBL31151124 0.84 PDK2 (0.55) PDK2KMT2APOLBTDP1
SCHEMBL5847201 0.84 PDK2 (0.55) PDK2KMT2APOLBTDP1
SCHEMBL5846670 0.84 PDK2 (0.55) PDK2KMT2APOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345301-B2 Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures MERCK PATENT GMBH (DE) 2008-03-18 US disclosed
US-20060208221-A1 Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-09-21 US disclosed