Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | INSR | P06213 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582860 | 0.76 | NPC1 (0.39) | CHEK1DRD1 | |
| SCHEMBL10015937 | 0.75 | AKT2 (0.51) | CHEK1TYK2KMT2A | |
| SCHEMBL28020115 | 0.75 | PDPK1 (0.50) | ADORA2AADORA1MGAMGAASI | |
| SCHEMBL2351250 | 0.72 | NPC1 (0.40) | GAACHEK1TYK2PARP2KMT2A | |
| SCHEMBL4582362 | 0.71 | ADORA2A (0.41) | ADORA2APARP1KMT2A | |
| SCHEMBL3617725 | 0.69 | TYMP (0.39) | GAACHEK1ILKKMT2A | |
| SCHEMBL2248431 | 0.68 | PDPK1 (0.43) | ADORA2AADORA1MGAMGAASI | |
| SCHEMBL11402984 | 0.68 | PTGES (0.44) | ADORA2AADORA1MGAMGAASI | |
| SCHEMBL16254413 | 0.68 | SRD5A1 (0.31) | PARP1 | |
| SCHEMBL10446010 | 0.68 | PDPK1 (0.40) | MGAMGAASIMGAM2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |