Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 5/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 2/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015937 | 0.88 | AKT2 (0.51) | NPC1LMNARAB9ACHEK1AKT2 | |
| SCHEMBL2351250 | 0.84 | NPC1 (0.40) | NPC1LMNARAB9ACHEK1AKT2 | |
| SCHEMBL14519431 | 0.81 | MAPK14 (0.44) | NPC1LMNARAB9AMAPK14CSNK1D | |
| SCHEMBL2352712 | 0.79 | PTGES (0.43) | NPC1LMNARAB9ACHEK1AKT2 | |
| SCHEMBL2352300 | 0.77 | AKT2 (0.49) | NPC1LMNARAB9ACHEK1AKT2 | |
| SCHEMBL4582141 | 0.76 | ADORA2A (0.42) | CHEK1DRD1 | |
| SCHEMBL2649168 | 0.76 | LMNA (0.58) | NPC1LMNARAB9AMAPK14CSNK1D | |
| SCHEMBL2354063 | 0.75 | MAPT (0.41) | MAPK14CHEK1AKT2DRD1 | |
| SCHEMBL4582362 | 0.75 | ADORA2A (0.41) | — | |
| SCHEMBL2352663 | 0.74 | MAPT (0.43) | LMNARAB9ACHEK1AKT2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |