Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 10/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024095 | 0.98 | HRH1 (0.47) | HRH1CXCR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28685512 | 0.93 | HRH1 (0.44) | HRH1CXCR4SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5845025 | 0.91 | HRH1 (0.43) | HRH1CXCR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3224199 | 0.87 | HRH1 (0.45) | HRH1SLC6A2SLC6A4SLC6A3TSHR | |
| Hydrochloric Acid SCHEMBL28631671 | 0.85 | HRH1 (0.44) | HRH1SLC6A2SLC6A4SLC6A3TSHR | |
| Hydrochloric Acid SCHEMBL5846124 | 0.85 | HRH1 (0.44) | HRH1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL23114268 | 0.85 | KCNA5 (0.47) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL10693275 | 0.85 | KCNA5 (0.47) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL27873703 | 0.85 | KCNA5 (0.47) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL26487309 | 0.85 | KCNA5 (0.47) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371852-B2 | Alkyl-linked nucleotide compositions | SERENEX, INC. (US) | 2008-05-13 | — | — | US | disclosed |
| EP-1585754-A2 | ALKYL-LINKED NUCLEOTIDE COMPOSITIONS | Serenex, Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| US-20040215009-A1 | Alkyl-linked nucleotide compositions | SERENEX, INC. (US) | 2004-10-28 | — | — | US | disclosed |
| WO-2004065566-A2 | ALKYL-LINKED NUCLEOTIDE COMPOSITIONS | SERENEX, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040215009-A1 | Alkyl-linked nucleotide compositions | NT5C3B, NUDT1, NT5C2 | HRH1 3847/4885CXCR4 501/4885SLC6A2 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.