Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 0.81 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.81 |
| ▸ | HTR2C | P28335 | 7/20 | 0.81 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5128659 | 0.99 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4583464 | 0.93 | MTNR1A (0.88) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL3328651 | 0.90 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL3328976 | 0.89 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL3326557 | 0.88 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4582729 | 0.88 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4582982 | 0.88 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| Hydrochloric Acid SCHEMBL5125205 | 0.88 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL4583437 | 0.87 | MTNR1A (0.83) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL5120175 | 0.87 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900723-A1 | New naphthalene derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2008-03-19 | — | — | EP | disclosed |