Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 17/20 | 1.00 |
| ▸ | HTR2C | P28335 | 7/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583464 | 0.94 | MTNR1A (0.88) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4583437 | 0.91 | MTNR1A (0.83) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL3326557 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4582369 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4582982 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4582729 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL3834460 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL5120175 | 0.88 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL3831576 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3328651 | 0.88 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137446-A1 | NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137446-A1 | NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MTNR1A, MTNR1B, AHR | MTNR1A 1/4885MTNR1B 2/4885HTR2C 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.