SCHEMBL4582380

SCHEMBL4582380

O=C(O)C12CC3CC(CC(C3)C1(C(=O)O)C(=O)O)C2

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.40
EPHX1 P07099 2/20 0.40
THRB P10828 1/20 0.36
CYP2C9 P11712 1/20 0.36
FAAH O00519 1/20 0.34
HSD11B1 P28845 2/20 0.33
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5832577 0.86 THRB (0.37) EPHX2EPHX1THRBCYP2C9FAAH
SCHEMBL5248488 0.78 THRB (0.36) EPHX2EPHX1THRBCYP2C9HSD11B1
SCHEMBL28699821 0.78 THRB (0.36) EPHX2EPHX1THRBCYP2C9FAAH
Hydrochloric Acid SCHEMBL27525501 0.77 THRB (0.35) EPHX2EPHX1THRBCYP2C9HSD11B1
Bromide SCHEMBL27511892 0.77 THRB (0.35) EPHX2EPHX1THRBCYP2C9HSD11B1
SCHEMBL31084436 0.77 THRB (0.35) EPHX2EPHX1THRBCYP2C9FAAH
SCHEMBL4711516 0.75 THRB (0.34) EPHX2EPHX1THRBCYP2C9HSD11B1
SCHEMBL2710253 0.75 EPHX2 (0.38) EPHX2EPHX1THRBCYP2C9FAAH
SCHEMBL905260 0.75 THRB (0.42) EPHX2EPHX1THRBCYP2C9ALDH1A1
SCHEMBL31084441 0.75 MAPK1 (0.36) EPHX2EPHX1THRBCYP2C9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114007689-A Polymorphs and co-crystals of a cardiac troponin activator 安进股份有限公司 2022-02-01 CN claimed
US-20060264667-A1 Adamantanetricarboxylic acid derivatives NAGANO SHINYA 2006-11-23 US claimed
US-7102027-B2 Adamantanetricarboxylic acid derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US claimed
EP-1505053-A1 Adamantanetricarboxylic acid derivatives Daicel Chemical Industries, Ltd. (JP) 2005-02-09 EP claimed
US-20040242923-A1 Adamantanetricarboxylic acid derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-02 US claimed
CN-122070344-A Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheet, and joined body 日东电工株式会社 2026-05-19 CN disclosed
EP-4674885-A1 POLYESTER, PRESSURE-SENSITIVE ADHESIVE AGENT COMPOSITION, PRESSURE-SENSITIVE ADHESIVE AGENT, PRESSURE-SENSITIVE ADHESIVE TAPE, AND PRESSURE-SENSITIVE ADHESIVE TAPE FOR ELECTRONIC MEMBERS Mitsubishi Chemical Corporation (JP) 2026-01-07 EP disclosed
US-20250361356-A1 POLYESTER, ADHESIVE COMPOSITION, ADHESIVE, ADHESIVE TAPE, AND ADHESIVE TAPE FOR ELECTRONIC COMPONENTS MITSUBISHI CHEMICAL CORPORATION (JP) 2025-11-27 US disclosed
US-20250188327-A1 ADHESIVE AGENT AND ADHESIVE SHEET MITSUBISHI CHEMICAL CORPORATION (JP) 2025-06-12 US disclosed
WO-2025121131-A1 DISASSEMBLY METHOD AND ADHESIVE SHEET 日東電工株式会社 2025-06-12 WO disclosed
WO-2025120959-A1 ADHESIVE SHEET AND LAMINATE 綜研化学株式会社 2025-06-12 WO disclosed
CN-120020189-A Adhesive sheet and portable electronic device 日东电工株式会社 2025-05-20 CN disclosed
US-20040242923-A1 Adamantanetricarboxylic acid derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-02 US disclosed
JP-2004292348-A ADAMANTANE TRICARBOXYLIC ACID DERIVATIVE DAICEL CHEM IND LTD 2004-10-21 JP disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-6794528-B2 HEAT RESISTANCE, FLAME RETARDERS, STABILIZERS; REACTING DIALCOHOL COMPOUND WITH A PHOSPHYL OXYCHLORIDE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-21 US disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed
JP-2004189697-A METHOD FOR MANUFACTURING POLYCARBOXYADAMANTANE DERIVATIVE DAICEL CHEM IND LTD 2004-07-08 JP disclosed
US-20030109736-A1 Phosphorus compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-12 US disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242923-A1 Adamantanetricarboxylic acid derivatives HCAR1, CA1, ALDH7A1 EPHX2 1271/4885EPHX1 980/4885THRB 2423/4885
US-20060264667-A1 Adamantanetricarboxylic acid derivatives CA1, HCAR1, ALDH7A1 EPHX2 1405/4885EPHX1 994/4885THRB 2537/4885
US-20030109736-A1 Phosphorus compound NR4A1, POLL, NR0B1 EPHX2 3620/4885EPHX1 3912/4885THRB 1241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.