Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | STK10 | O94804 | 2/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583119 | 0.88 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL4582842 | 0.86 | PTGS2 (0.39) | PTGS2PTGS1HCAR3HCAR2 | |
| SCHEMBL4584165 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1GSK3B | |
| SCHEMBL4582575 | 0.82 | PTGS2 (0.51) | PTGS2PTGS1HSP90AA1HSP90AB1PGR | |
| SCHEMBL4582869 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1HCAR3HCAR2 | |
| SCHEMBL4583249 | 0.81 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL4582558 | 0.80 | PTGS2 (0.34) | PTGS2PTGS1 | |
| SCHEMBL4607900 | 0.80 | PTGS2 (0.57) | PTGS2PTGS1HCAR3HCAR2 | |
| SCHEMBL4581586 | 0.78 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL4591894 | 0.78 | PTGS2 (0.44) | PTGS2PTGS1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |