Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583198 | 0.86 | PTGS2 (0.52) | PTGS2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL4583426 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1MAPTKMT2AMAPK14 | |
| SCHEMBL4582348 | 0.84 | PTGS2 (0.47) | PTGS2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL4582564 | 0.82 | PTGS2 (0.43) | PTGS2PTGS1HSP90AA1HSP90AB1PGR | |
| SCHEMBL4583796 | 0.78 | PTGS2 (0.52) | PTGS2ALDH1A1KDM4ESMN1; SMN2PTGS1 | |
| SCHEMBL4583216 | 0.75 | PTGS2 (0.52) | PTGS2PTGS1KMT2A | |
| SCHEMBL2454166 | 0.75 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL4581906 | 0.75 | PTGS2 (0.47) | PTGS2PTGS1MAPT | |
| SCHEMBL3617636 | 0.73 | PTGS2 (0.50) | PTGS2ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4583119 | 0.70 | PTGS2 (0.39) | PTGS2PTGS1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |