Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464951 | 0.79 | OPRM1 (0.42) | OPRM1PLA2G1BPLA2G2ASPHK1TP53 | |
| SCHEMBL15132109 | 0.75 | PLA2G1B (0.39) | OPRM1PLA2G1BPLA2G2ASPHK1TP53 | |
| SCHEMBL30996352 | 0.73 | OPRM1 (0.37) | OPRM1PLA2G1BPLA2G2ASPHK1TP53 | |
| SCHEMBL9748043 | 0.73 | PLA2G1B (0.33) | OPRM1PLA2G1BPLA2G2AMMP1MMP2 | |
| SCHEMBL10583794 | 0.73 | MMP1 (0.36) | OPRM1MMP1MMP2MMP3MMP8 | |
| SCHEMBL865548 | 0.73 | MMP1 (0.36) | OPRM1PLA2G1BPLA2G2ATP53MMP1 | |
| SCHEMBL9873123 | 0.72 | OPRM1 (0.46) | OPRM1PLA2G1BPLA2G2ASPHK1TP53 | |
| SCHEMBL234773 | 0.72 | PLA2G1B (0.35) | OPRM1PLA2G1BPLA2G2AMMP1MMP2 | |
| SCHEMBL24733047 | 0.71 | PLA2G1B (0.36) | OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL12212012 | 0.71 | OPRM1 (0.36) | OPRM1PLA2G1BPLA2G2ASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080107894-A1 | Polysilazane-Based Coating Solution And The Use Thereof For Coating Films, Especially Polymer Films | CLARIANT FINANCE (BVI) LIMITED (VG) | 2008-05-08 | — | — | US | disclosed |