Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.38 |
| ▸ | USP19 | O94966 | 1/20 | 0.38 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45822 | 0.90 | STAT3 (0.42) | USP1USP19UCHL3ALDH1A1STAT3 | |
| SCHEMBL45659 | 0.81 | ALDH1A1 (0.33) | USP1USP19UCHL3ALDH1A1STAT3 | |
| SCHEMBL15024251 | 0.76 | ALDH1A1 (0.46) | ALDH1A1STAT3NPC1MAPTCASP3 | |
| SCHEMBL15024389 | 0.74 | ELANE (0.35) | ALDH1A1STAT3MAPTMAOBMEN1 | |
| SCHEMBL13924975 | 0.68 | ALDH1A1 (0.46) | UCHL3ALDH1A1STAT3NPC1MAPT | |
| SCHEMBL45638 | 0.66 | ALDH1A1 (0.53) | USP1USP19ALDH1A1STAT3NPC1 | |
| SCHEMBL45671 | 0.66 | ALDH1A1 (0.45) | USP1USP19UCHL3ALDH1A1STAT3 | |
| SCHEMBL18030270 | 0.65 | STAT3 (0.58) | ALDH1A1STAT3NPC1MAPTRAB9A | |
| SCHEMBL13924797 | 0.65 | ALDH1A1 (0.41) | USP1USP19ALDH1A1STAT3NPC1 | |
| SCHEMBL15026353 | 0.65 | ALDH1A1 (0.44) | USP1USP19UCHL3ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024818-A1 | NOVEL ANPHTHOQUINONES FOR DISEASE THERAPIES | ZHOUSHAN HAIZHONGZHOU XINSHENG PHARMACEUTICALS CO., LTD. (CN) | 2012-03-01 | — | — | WO | disclosed |