Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | USP1 | O94782 | 1/20 | 0.43 |
| ▸ | USP19 | O94966 | 1/20 | 0.43 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45702 | 0.90 | MAPT (0.38) | ALDH1A1STAT3USP1USP19UCHL3 | |
| SCHEMBL15024250 | 0.85 | ALDH1A1 (0.48) | ALDH1A1STAT3MEN1KMT2APKLR | |
| SCHEMBL15024455 | 0.82 | TLR9 (0.38) | ALDH1A1MEN1KMT2APTGS2MAPT | |
| SCHEMBL45695 | 0.74 | STAT3 (0.56) | ALDH1A1STAT3USP1USP19MEN1 | |
| SCHEMBL45822 | 0.74 | STAT3 (0.42) | ALDH1A1STAT3USP1USP19UCHL3 | |
| SCHEMBL45647 | 0.74 | STAT3 (0.47) | ALDH1A1STAT3USP1USP19UCHL3 | |
| SCHEMBL16167166 | 0.72 | STAT3 (0.56) | ALDH1A1STAT3USP1USP19UCHL3 | |
| SCHEMBL45711 | 0.72 | PTGS2 (0.39) | ALDH1A1STAT3PTGS2PTGS1 | |
| SCHEMBL15026352 | 0.70 | USP8 (0.35) | ALDH1A1STAT3USP1USP19UCHL3 | |
| Anthraquinone SCHEMBL28557258 | 0.69 | SMN1; SMN2 (0.52) | ALDH1A1MEN1KMT2APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871802-B2 | Naphthoquinones for disease therapies | ZHOUSHAN HAIZHONGZHOU XINSHENG PHARMACEUTICALS CO., LTD. (CN) | 2014-10-28 | — | — | US | disclosed |
| US-20130150437-A1 | NAPHTHOQUINONES FOR DISEASE THERAPIES | ZHOUSHAN HAIZHONGZHOU XINSHENG PHARMACEUTICALS CO., LTD. (CN) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150437-A1 | NAPHTHOQUINONES FOR DISEASE THERAPIES | NQO1, NME2, CYP27B1 | ALDH1A1 282/4885STAT3 1764/4885USP1 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.