Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 7/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595933 | 1.00 | BMP1 (0.41) | BMP1PAK1MMP12P2RX7CYP2C9 | |
| SCHEMBL1595935 | 1.00 | BMP1 (0.41) | BMP1PAK1MMP12P2RX7CYP2C9 | |
| SCHEMBL2782850 | 0.84 | TSHR (0.43) | BMP1 | |
| SCHEMBL1596956 | 0.84 | TSHR (0.43) | BMP1 | |
| SCHEMBL1596960 | 0.84 | TSHR (0.43) | BMP1 | |
| SCHEMBL1596337 | 0.80 | BMP1 (0.49) | BMP1 | |
| SCHEMBL1596338 | 0.80 | BMP1 (0.49) | BMP1 | |
| SCHEMBL1596333 | 0.80 | BMP1 (0.49) | BMP1 | |
| SCHEMBL1596984 | 0.78 | ALDH1A1 (0.47) | BMP1MMP12RAB9A | |
| SCHEMBL1596987 | 0.78 | ALDH1A1 (0.47) | BMP1MMP12RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |