Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039332 | 0.95 | MMP9 (0.35) | RENTMEM97SIGMAR1PDE4B | |
| SCHEMBL3908978 | 0.95 | MMP9 (0.35) | RENTMEM97SIGMAR1PDE4B | |
| SCHEMBL4582363 | 0.93 | REN (0.35) | RENTMEM97SIGMAR1PDE4BKLK7 | |
| SCHEMBL3907512 | 0.92 | REN (0.38) | RENCYSLTR2CYSLTR1GRM5TMEM97 | |
| SCHEMBL1036379 | 0.92 | REN (0.39) | RENCYSLTR2CYSLTR1GRM5TMEM97 | |
| SCHEMBL3902388 | 0.91 | REN (0.36) | RENCYSLTR2CYSLTR1GRM5FFAR1 | |
| SCHEMBL3905577 | 0.90 | REN (0.40) | RENCYSLTR2CYSLTR1GRM5TMEM97 | |
| SCHEMBL3914858 | 0.90 | REN (0.36) | RENCYSLTR2CYSLTR1GRM5FFAR1 | |
| SCHEMBL3902352 | 0.90 | REN (0.36) | RENCYSLTR2CYSLTR1GRM5FFAR1 | |
| SCHEMBL2343571 | 0.89 | MMP9 (0.37) | RENPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |