Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924051 | 1.00 | CYP2C9 (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2923691 | 0.95 | FKBP1A (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2916770 | 0.95 | FKBP1A (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2922529 | 0.94 | LMNA (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2915884 | 0.94 | CYP2C9 (0.35) | CYP2C9LMNASMN1; SMN2KMT2ATP53 | |
| SCHEMBL1038932 | 0.94 | CYP2C9 (0.35) | CYP2C9LMNASMN1; SMN2KMT2ATP53 | |
| SCHEMBL2923087 | 0.93 | LMNA (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2919065 | 0.93 | KMT2A (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2922614 | 0.93 | FKBP1A (0.34) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL2921489 | 0.93 | SMN1; SMN2 (0.35) | CYP2C9LMNASMN1; SMN2KMT2AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |