SCHEMBL4583256

SCHEMBL4583256

O=[N+]([O-])c1ccccc1-c1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
TDP1 Q9NUW8 3/20 0.59
HPGD P15428 2/20 0.55
PTPN1 P18031 1/20 0.51
MAPT P10636 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MAPK1 P28482 2/20 0.47
S100A4 P26447 2/20 0.47
PTPRC P08575 1/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 2/20 0.47
HSD11B1 P28845 1/20 0.47
EIF4E P06730 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MGAM O43451 1/20 0.45
GAA P10253 1/20 0.45
SI P14410 1/20 0.45
MGAM2 Q2M2H8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28242473 0.89 ALDH1A1 (0.49) ALDH1A1TDP1HPGDPTPN1MAPT
SCHEMBL1287837 0.87 ALDH1A1 (0.74) ALDH1A1TDP1HPGDPTPN1L3MBTL1
SCHEMBL30535903 0.87 ALDH1A1 (0.74) ALDH1A1TDP1HPGDPTPN1L3MBTL1
SCHEMBL30987815 0.84 ALDH1A1 (0.71) ALDH1A1TDP1HPGDPTPN1L3MBTL1
SCHEMBL29337140 0.84 ALDH1A1 (0.71) ALDH1A1TDP1HPGDPTPN1L3MBTL1
Ammonia Solution, Strong SCHEMBL9060371 0.84 ALDH1A1 (0.71) ALDH1A1TDP1HPGDPTPN1L3MBTL1
SCHEMBL28775421 0.83 MAPK1 (0.55) ALDH1A1HPGDMAPTL3MBTL1MAPK1
SCHEMBL1558206 0.83 HSD11B1 (0.66) ALDH1A1TDP1HPGDPTPN1MAPT
SCHEMBL28927361 0.83 HPGD (0.47) ALDH1A1TDP1HPGDPTPN1MAPT
SCHEMBL28927334 0.83 MEN1 (0.48) ALDH1A1TDP1HPGDPTPN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122032423-A Catalyst for continuous production of 4' -chloro-2-aminobiphenyl, reaction system and process 厦门嘉氢科技有限公司 2026-05-15 CN claimed
CN-112358402-B Preparation method of 4' -chloro-2-nitrobiphenyl 湖南海利常德农药化工有限公司 2022-11-29 CN claimed
CN-110325513-A The method for preparing substituted biphenyl 巴斯夫欧洲公司 2019-10-11 CN claimed
CN-109912425-A A kind of preparation method of the chloro- 2 nitro biphenyl of 4`- 京博农化科技有限公司 2019-06-21 CN claimed
CN-109563023-A The method for preparing substituted biphenyl 巴斯夫欧洲公司 2019-04-02 CN claimed
CN-109553535-A A kind of method that one kettle way prepares the chloro- 2`- nitrobiphenyl of 4- 宁波赜军医药科技有限公司 2019-04-02 CN claimed
CN-105017025-B The preparation method of one kind 4 '-chloro- 2 nitro biphenyl 浙江省化工研究院有限公司 2018-06-12 CN claimed
CN-105061296-B A kind of preparation method of 2 substituted carbazole class compound 张家港江苏科技大学产业技术研究院 2018-02-06 CN claimed
CN-104725303-B The synthetic method of one kind 2 chlorine N (base of 4 ' chlordiphenyl 2) niacinamide 西安近代化学研究所 2017-09-08 CN claimed
CN-105732392-A Method for preparing 4'-chloro-2-nitrobiphenyl 天津市均凯化工科技有限公司 2016-07-06 CN claimed
CN-105218378-A Prepare the method for substituted biphenyl BASF SE 2016-01-06 CN claimed
CN-104725303-A Synthetic method of 2-chloro-N-(4'-chlorodiphenyl-2-yl) nicotinamide XIAN MODERN CHEMISTRY RES INST 2015-06-24 CN claimed
CN-103539679-B Method for preparing 4'-chloro-2-aminobiphenyl through palladium/carbon catalysis JUNKAI TIANJIN CHEMICAL CO LTD 2015-05-13 CN claimed
CN-104478725-A Method for preparing 4'-chloro-2-nitro biphenyl JUNKAI TIANJIN CHEMICAL CO LTD 2015-04-01 CN claimed
CN-104478797-A Preparation method of nicotinamide fungicide namely boscalid SUZHOU TOKIND CHEMICAL CO LTD 2015-04-01 CN claimed
CN-103539679-A Method for preparing 4'-chloro-2-aminobiphenyl through palladium/carbon catalysis JUNKAI TIANJIN CHEMICAL CO LTD 2014-01-29 CN claimed
CN-102076651-A Process for preparing substituted biphenyls BASF SE 2011-05-25 CN claimed
CN-122102915-A Preparation method of boscalid intermediate 4' -chloro-2-nitrobiphenyl 2026-05-29 CN disclosed
EP-1175406-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2002-01-30 EP disclosed
WO-2000066563-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2000-11-09 WO disclosed