Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40038 | 0.75 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29927048 | 0.75 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL153460 | 0.69 | NPC1 (0.42) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL936843 | 0.67 | MEN1 (0.40) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4087849 | 0.66 | NPC1 (0.43) | NPC1RAB9AKMT2AMEN1HTT | |
| SCHEMBL1812180 | 0.66 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3257688 | 0.66 | HPGD (0.48) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5172196 | 0.62 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AMEN1HTT | |
| SCHEMBL1802165 | 0.62 | CES2 (0.50) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8497069 | 0.62 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056534-B1 | EXPANDABLE VINYL AROMATIC POLYMERIC COMPOSITIONS | VERSALIS SPA (IT) | 2019-04-10 | — | — | EP | claimed |
| EP-1448612-B1 | VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE | POLIMERI EUROPA SPA (IT) | 2008-12-31 | — | — | EP | claimed |
| JP-3803880-B2 | — | — | 2006-08-02 | — | — | JP | claimed |
| EP-1448612-A1 | VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE | Polimeri Europa S.p.A. (IT) | 2004-08-25 | — | — | EP | claimed |
| WO-2003046016-A1 | VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE | POLIMERI EUROPA S.P.A. (IT) | 2003-06-05 | — | — | WO | claimed |
| EP-0783543-A4 | MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS | KNAUS DENNIS A (US) | 1998-11-11 | — | — | EP | claimed |
| EP-0783543-A1 | MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS | Knaus, Dennis A. (US) | 1997-07-16 | — | — | EP | claimed |
| US-5589519-A | Process of extruding lightly crosslinked polyolefin foam | KNAUS DENNIS A (US) | 1996-12-31 | — | — | US | claimed |
| WO-1996010600-A1 | MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS | KNAUS DENNIS A (US) | 1996-04-11 | — | — | WO | claimed |
| EP-0004050-B2 | FLAME-PROTECTED EXPANDABLE STYRENE POLYMERS USEFUL IN FOAM PREPARATION | BASF Aktiengesellschaft (DE) | 1986-09-10 | — | — | EP | claimed |
| EP-0004050-B1 | FLAME-PROTECTED EXPANDABLE STYRENE POLYMERS USEFUL IN FOAM PREPARATION | BASF Aktiengesellschaft (DE) | 1981-11-25 | — | — | EP | claimed |
| EP-2495277-B1 | FOAMABLE POLYSTYRENE RESIN PARTICLES AND PROCESS FOR PRODUCTION THEREOF, POLYSTYRENE RESIN PREFOAMED PARTICLES, POLYSTYRENE RESIN FOAM-MOLDED ARTICLE, HEAT-INSULATING MATERIAL FOR BUILDING MATERIAL, BANKING MEMBER, AND VEHICLE INTERIOR MATERIAL | SEKISUI PLASTICS (JP) | 2021-03-24 | — | — | EP | disclosed |
| US-10696807-B2 | Expandable vinyl aromatic polymeric compositions | VERSALIS S.P.A. (IT) | 2020-06-30 | — | — | US | disclosed |
| US-10358538-B2 | Foamable polystyrene resin particles and polystyrene resin prefoamed particles | SEKISUI PLASTICS CO., LTD. (JP) | 2019-07-23 | — | — | US | disclosed |
| EP-3056534-B1 | EXPANDABLE VINYL AROMATIC POLYMERIC COMPOSITIONS | VERSALIS SPA (IT) | 2019-04-10 | — | — | EP | disclosed |
| US-4198486-A | MELTING WITH ALUMINUM HYDROXIDE AND FLAMEPROOFING AGENTS, HOMOGENIZING, EXTRUSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4192922-A | Finely divided expandable styrene polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-03-11 | — | — | US | disclosed |
| US-4029614-A | Particulate expandable styrene polymers having good processability | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |
| US-3965214-A | DECABROMOBIPHENYL, ANTIMONY OXIDE | MICHIGAN CHEMICAL CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
| US-3962164-A | A DIPHENYL, ANTIMONY TRIOXIDE OR OXYCHLORIDE, ORGANO-CHLORO, AROMATIC BROMINE | CHEMISCHE FABRIK KALK GMBH (DT) | 1976-06-08 | — | — | US | disclosed |