Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58127 | 0.85 | HSD17B10 (0.54) | HSD17B10TSHRSMN1; SMN2TDP1MAPT | |
| SCHEMBL57882 | 0.80 | TSHR (0.40) | HSD17B10TSHRTDP1MAPTALDH1A1 | |
| SCHEMBL2767392 | 0.79 | — | — | |
| SCHEMBL6670326 | 0.77 | HSD17B10 (0.50) | HSD17B10TSHRSMN1; SMN2TDP1MAPT | |
| SCHEMBL457758 | 0.76 | ALDH1A1 (0.41) | HSD17B10TSHRSMN1; SMN2TDP1MAPT | |
| SCHEMBL429269 | 0.76 | ALDH1A1 (0.58) | HSD17B10SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL158733 | 0.75 | GPR35 (0.47) | HSD17B10TSHRSMN1; SMN2TDP1MAPT | |
| SCHEMBL407090 | 0.75 | TDP1 (0.48) | HSD17B10TSHRSMN1; SMN2TDP1MAPT | |
| SCHEMBL2783828 | 0.75 | TDP1 (0.48) | HSD17B10TSHRSMN1; SMN2TDP1MAPT | |
| SCHEMBL29172280 | 0.75 | PARP1 (0.37) | HSD17B10TSHRTDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | claimed |
| EP-1131290-B1 | PIPERIDINE CCR-3 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-02-20 | — | — | EP | claimed |
| CN-1281604-C | Substituted pyrazole compounds | TEIKOKU HORMONE MFG CO LTD (JP) | 2006-10-25 | — | — | CN | claimed |
| EP-0903349-B1 | CCR-3 receptor antagonists | HOFFMANN LA ROCHE (CH) | 2006-01-04 | — | — | EP | claimed |
| EP-1188754-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | TEIKOKU HORMONE MFG CO LTD (JP) | 2005-06-01 | — | — | EP | claimed |
| CN-1560051-A | Substituted pyrazole compounds | �۹���ҩ��ʽ���� | 2005-01-05 | — | — | CN | claimed |
| US-20040266782-A1 | Cyclic amine derivatives-CCR-3 receptor antagonists | GONG LEYI (US) | 2004-12-30 | — | — | US | claimed |
| CN-1178931-C | Substituted pyrazole compounds | �۹���ҩ��ʽ���� | 2004-12-08 | — | — | CN | claimed |
| US-6815442-B2 | A PHENOXY-ALKYL-QUINOXALINONE DERIVATIVES FOR INHIBITING DRUG TRANSPORT PROTEINS THAT EFFLUX THERAPEUTIC AGENTS FROM CELLS; SYNERGISTIC | THE PENN STATE RESEARCH FOUNDATION | 2004-11-09 | — | — | US | claimed |
| US-6683074-B1 | PYRROLIDINYL, PIPERAZINYL AND AZEPINYL DERIVATIVES; INFLAMMATORY OR ALLERGIC DISEASES | SYNTEX (U.S.A.) LLC | 2004-01-27 | — | — | US | claimed |
| WO-1991000294-A1 | MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1991-01-10 | — | — | WO | claimed |
| US-4885286-A | LONG LASTING; CARBAMATE PHOSPHORYLATION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-12-05 | — | — | US | claimed |
| EP-0327663-A1 | Novel phosphonamidothionate derivatives and their use as pesticides | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-08-16 | — | — | EP | claimed |
| US-4818748-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | claimed |
| EP-0128462-B1 | NOVEL BENZOTHIAZEPINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1989-03-22 | — | — | EP | claimed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | claimed |
| US-4521430-A | VASODILATOR, ANTIISCHEMIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1985-06-04 | — | — | US | claimed |
| EP-0128462-A1 | Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1984-12-19 | — | — | EP | claimed |
| US-4118561-A | ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-10-03 | — | — | US | claimed |
| US-3966921-A | NEMATOCIDES | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266782-A1 | Cyclic amine derivatives-CCR-3 receptor antagonists | CCR3, CCR1, CCRL2 | HSD17B10 3997/4885TSHR 631/4885SMN1; SMN2 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.