Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 9/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4582966 | 0.99 | ADA (0.56) | ADATOP2AHTR3AALDH1A1CEPT1 | |
| SCHEMBL4582826 | 0.92 | ADA (0.59) | ADAHTR3ACEPT1 | |
| Hydrochloric Acid SCHEMBL4583285 | 0.91 | ADA (0.67) | ADAHTR3AALDH1A1KDM4ENPC1 | |
| SCHEMBL4583595 | 0.91 | ADA (0.55) | ADAALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL4583484 | 0.91 | ADA (0.57) | ADAPKMNPC1RAB9A | |
| SCHEMBL4583380 | 0.91 | ADA (0.55) | ADAHTR3AALDH1A1KDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL4585538 | 0.90 | ADA (0.54) | ADAALDH1A1KDM4EPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL4583542 | 0.90 | ADA (0.54) | ADAHTR3AALDH1A1KDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL4584745 | 0.90 | ADA (0.56) | ADAPKMNPC1RAB9A | |
| SCHEMBL4584348 | 0.89 | ADA (0.54) | ADAALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317107-B2 | Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity | ASTELLAS PHARMA INC. (JP) | 2008-01-08 | — | — | US | claimed |
| EP-1474421-A1 | IMIDAZOLE 4-CARBOXAMIDE COMPOUNDS WITH ADENOSINE DEAMINASE INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-10 | — | — | EP | claimed |
| WO-2003068768-A1 | IMIDAZOLE 4-CARBOXAMIDE COMPOUNDS WITH ADENOSINE DEAMINASE INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-21 | — | — | WO | claimed |
| US-7317107-B2 | Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity | ASTELLAS PHARMA INC. (JP) | 2008-01-08 | — | — | US | disclosed |
| US-20050159462-A1 | Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity | ASTELLAS PHARMA INC. (JP) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159462-A1 | Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity | ADA, AMPD2, AMPD1 | ADA 1/4885TOP2A 860/4885HTR3A 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.