Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1517823 | 0.94 | REN (0.31) | RENCYP2C9 | |
| SCHEMBL1517821 | 0.94 | REN (0.31) | RENCYP2C9 | |
| SCHEMBL1037150 | 0.93 | LMNA (0.34) | LMNASMN1; SMN2RENCYP2C9PKM | |
| SCHEMBL2915854 | 0.92 | CYP2C9 (0.34) | LMNASMN1; SMN2RENCYP2C9PKM | |
| SCHEMBL2924529 | 0.92 | CYP2C9 (0.34) | LMNASMN1; SMN2RENCYP2C9PKM | |
| SCHEMBL1038932 | 0.92 | CYP2C9 (0.35) | LMNASMN1; SMN2CYP2C9PKMALDH1A1 | |
| SCHEMBL2915884 | 0.92 | CYP2C9 (0.35) | LMNASMN1; SMN2CYP2C9PKMALDH1A1 | |
| SCHEMBL2390299 | 0.92 | REN (0.31) | REN | |
| SCHEMBL2390303 | 0.92 | REN (0.31) | REN | |
| SCHEMBL1036293 | 0.91 | CYP2C9 (0.35) | LMNASMN1; SMN2RENCYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |