Ethylene Glycol

Ethylene Glycol

SCHEMBL4583804

O=C(O)c1c(F)c(F)c(F)c(F)c1F.O=C(O)c1c(F)c(F)c(F)c(F)c1F.OCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PKM P14618 1/20 0.39
MEN1 O00255 6/20 0.37
KMT2A Q03164 6/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
GAA P10253 1/20 0.35
MAPK1 P28482 3/20 0.35
HSD17B10 Q99714 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
RECQL P46063 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203915 0.88 CES2 (0.43) TSHRHTTSMN1; SMN2PKMMEN1
Monoethanolamine SCHEMBL1833733 0.87 TSHR (0.38) TSHRHTTSMN1; SMN2PKMMEN1
Ethylene Glycol SCHEMBL2167363 0.87 HTT (0.41) TSHRHTTSMN1; SMN2PKMMEN1
SCHEMBL2150002 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1
Hydrochloric Acid SCHEMBL11033629 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1
SCHEMBL28389339 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1
Ammonia Solution, Strong SCHEMBL20291864 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1
SCHEMBL16756190 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1
SCHEMBL336420 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1
Ammonia Solution, Strong SCHEMBL11055563 0.85 CES2 (0.42) TSHRHTTSMN1; SMN2PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530269-B2 Manufacture of a polymer device CAMBRIDGE ENTERPRISE LTD (GB) 2013-09-10 US disclosed
EP-1631995-B1 MANUFACTURE OF A POLYMER DEVICE CAMBRIDGE ENTPR LTD (GB) 2008-07-16 EP disclosed
US-20070172978-A1 Manufacture of a polymer device CAMBRIDGE UNIVERSITY TECHNICAL SERVICE LIMITED (GB) 2007-07-26 US disclosed