Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL4584735 | 0.90 | HTT (0.38) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| Ethylene Glycol SCHEMBL4583804 | 0.87 | TSHR (0.41) | TSHRALDH1A1HTTSMN1; SMN2PKM | |
| Hydroxyamine SCHEMBL31050881 | 0.82 | CES2 (0.40) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| SCHEMBL203915 | 0.82 | CES2 (0.43) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| Ammonia Solution, Strong SCHEMBL20291864 | 0.79 | CES2 (0.42) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| SCHEMBL16756190 | 0.79 | CES2 (0.42) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| SCHEMBL2150002 | 0.79 | CES2 (0.42) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| Hydrochloric Acid SCHEMBL11033629 | 0.79 | CES2 (0.42) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| SCHEMBL336420 | 0.79 | CES2 (0.42) | TSHRHTTSMN1; SMN2PKMMEN1 | |
| SCHEMBL28389339 | 0.79 | CES2 (0.42) | TSHRHTTSMN1; SMN2PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |