Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.47 |
| ▸ | CYP51A1 | Q16850 | 6/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584050 | 1.00 | ADRB3 (0.47) | ADRB3ADRB1ADRB2CYP51A1KCNA5 | |
| SCHEMBL4584190 | 0.94 | ADRB3 (0.46) | ADRB3ADRB1ADRB2CYP51A1KCNA5 | |
| SCHEMBL4584186 | 0.94 | ADRB3 (0.46) | ADRB3ADRB1ADRB2CYP51A1KCNA5 | |
| SCHEMBL4558402 | 0.89 | CYP51A1 (0.47) | ADRB3ADRB1ADRB2CYP51A1 | |
| SCHEMBL4558403 | 0.89 | CYP51A1 (0.47) | ADRB3ADRB1ADRB2CYP51A1 | |
| SCHEMBL4584835 | 0.86 | MEN1 (0.48) | HDAC1HDAC6 | |
| SCHEMBL4584829 | 0.86 | MEN1 (0.48) | HDAC1HDAC6 | |
| SCHEMBL1622683 | 0.84 | CYP51A1 (0.46) | ADRB3ADRB1ADRB2CYP51A1KCNA5 | |
| SCHEMBL4583968 | 0.80 | MEN1 (0.47) | HDAC3 | |
| SCHEMBL4583973 | 0.80 | MEN1 (0.47) | HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20080039506-A1 | Aminoalcohol Derivatives | ASTELLAS PHARMA INC. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1791811-A1 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006033446-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2006-03-30 | — | — | WO | disclosed |
| US-20050137236-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137236-A1 | Aminoalcohol derivatives | GPR39, PRMT9, CHRM2 | ADRB3 86/4885ADRB1 70/4885ADRB2 58/4885 |
| US-20080039506-A1 | Aminoalcohol Derivatives | HRH4, HRH2, CBR3 | ADRB3 40/4885ADRB1 19/4885ADRB2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.