SCHEMBL7749757

SCHEMBL7749757

Cc1cc(Cc2c(C)ccc(C(C)(C)C)c2O)c(O)c(Cc2c(C)ccc(C(C)(C)C)c2O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 6/20 0.60
CYP2C9 P11712 5/20 0.60
HIF1A Q16665 5/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
HSPA5 P11021 2/20 0.57
CYP2D6 P10635 2/20 0.54
HSD17B10 Q99714 1/20 0.54
AMY1A P0DUB6 1/20 0.45
ALDH1A1 P00352 4/20 0.44
CA2 P00918 3/20 0.44
POLB P06746 1/20 0.44
TYR P14679 1/20 0.44
TP53 P04637 3/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CYP1A2 P05177 3/20 0.37
PTGS2 P35354 2/20 0.35
PTGS1 P23219 1/20 0.35
TSHR P16473 4/20 0.34
CYP3A4 P08684 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753473 0.84 CYP2C19 (0.50) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL29650379 0.84 CYP2C19 (0.50) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL29290543 0.81 AMY1A (0.56) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL30375451 0.81 AMY1A (0.56) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL4584268 0.80 HSPA5 (0.66) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL29650132 0.80 HSPA5 (0.66) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL28277442 0.80 HSPA5 (0.41) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL20608349 0.79 HSPA5 (0.43) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL12128513 0.79 AMY1A (0.46) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5
SCHEMBL2165152 0.77 GABRA1 (0.50) CYP2C19CYP2C9HIF1ASMN1; SMN2HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001023498-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF STABILIZER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2001-04-05 WO disclosed