SCHEMBL4584269

SCHEMBL4584269

COP(O)Oc1c(C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
RARG P13631 1/20 0.33
RXRA P19793 1/20 0.33
PPARG P37231 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
HTR1D P28221 2/20 0.31
HTR1B P28222 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519938 0.91 POLB (0.36) POLBRARGRXRAPPARGALDH1A1
SCHEMBL29413912 0.91 POLB (0.36) POLBRARGRXRAPPARGALDH1A1
SCHEMBL29130833 0.85 POLB (0.32) POLBGABRA1GABRB2HTR1DHTR1B
SCHEMBL28542242 0.84 POLB (0.36) POLBRARGRXRAPPARGALDH1A1
SCHEMBL29390482 0.83 POLB (0.35) POLBRARGRXRAPPARGALDH1A1
SCHEMBL194523 0.83 POLB (0.35) POLBRARGRXRAPPARGALDH1A1
SCHEMBL3679680 0.83 RXRA (0.34) POLBRARGRXRAPPARGTSHR
SCHEMBL11421838 0.82 GABRA1 (0.38) POLBRARGRXRAPPARGALDH1A1
SCHEMBL29130830 0.81 POLB (0.34) POLBRARGRXRAPPARGALDH1A1
SCHEMBL11431393 0.80 GABRA1 (0.37) POLBRARGRXRAPPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101798399-A Polymer stabilizer SUMITOMO CHEMICAL CO 2010-08-11 CN disclosed
EP-1877481-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS Sun Ace Kakoh (Pte.) Ltd. (SG) 2008-01-16 EP disclosed
US-7255814-B2 Flame retardant and stabilizer combined for thermoplastics polymers CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-14 US disclosed
WO-2006110112-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2006-10-19 WO disclosed
US-20040227130-A1 Flame retardant and stabilizer combined for thermoplastics polymers CLARIANT GMBH 2004-11-18 US disclosed
CN-1165384-C Process for prodn. of strongly adherent surface-coatings by plasma-activated grafting �������⻯ѧƷ�ع����޹�˾ 2004-09-08 CN disclosed
CN-1473152-A Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same CYTEC 2004-02-04 CN disclosed
CN-1398205-A Method for producing strongly adherent surface coatings by plasma activated grafting CIBA SC HOLDING AG (CH) 2003-02-19 CN disclosed
CN-1176280-A Stabilizers for powder coatings CIBA SC HOLDING AG (CH) 1998-03-18 CN disclosed
CN-1036928-C Oligomeric HALS phosphites and HALS phosphonites as stabilisers CIBA SPECIAL CHEMICAL CO LTD (CH) 1998-01-07 CN disclosed
CN-1092785-A Oligomeric HALS phosphorous acid ester and HALS phosphinate with used as stabilizers CIBA GEIGY AG (CH) 1994-09-28 CN disclosed