SCHEMBL4584389

SCHEMBL4584389

Cc1csc(-c2nc3cccc(C(CC[C@H](C)O[Si](C)(C)C(C)(C)C)n4cnc(C(N)=O)c4)c3o2)c1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADA P00813 9/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4585295 0.90 ADA (0.44) ADA
SCHEMBL4584029 0.88 ADA (0.46) ADA
SCHEMBL4584056 0.88 ADA (0.50) ADA
SCHEMBL4584396 0.87 ADA (0.40) ADA
SCHEMBL4584977 0.84 ADA (0.59) ADA
SCHEMBL4584649 0.83 ADA (0.49) ADA
SCHEMBL4584391 0.82 ADA (0.55) ADA
SCHEMBL4584306 0.78 ADA (0.50) ADA
Hydrochloric Acid SCHEMBL4583751 0.78 ADA (0.49) ADA
SCHEMBL4584033 0.76 ADA (0.70) ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7317107-B2 Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity ASTELLAS PHARMA INC. (JP) 2008-01-08 US disclosed
US-20050159462-A1 Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity ASTELLAS PHARMA INC. (JP) 2005-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159462-A1 Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity ADA, AMPD2, AMPD1 ADA 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.