SCHEMBL4584539

SCHEMBL4584539

CC(C)[Si](C#Cc1c2cc3ccccc3cc2c(C#C[Si](C(C)C)(C(C)C)C(C)C)c2cc3sccc3cc12)(C(C)C)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648632 0.94 DYRK1A (0.33) DYRK1A
SCHEMBL650203 0.94 DYRK1A (0.33) DYRK1A
SCHEMBL12591168 0.89 DYRK1A (0.31) DYRK1A
SCHEMBL12591167 0.86
SCHEMBL336442 0.85 CACNA2D1 (0.37)
SCHEMBL29360481 0.85 CACNA2D1 (0.37)
SCHEMBL12590007 0.85 ELANE (0.32)
SCHEMBL18267813 0.84 CACNA2D1 (0.36)
SCHEMBL1270205 0.82 CACNA2D1 (0.35)
SCHEMBL14514097 0.82 CACNA2D1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-7935960-B2 organic field effect transistors; introducing asymmetry into the polyacene derivative affects its solid-state order; combining with organic binder resin results in little or no reduction in charge mobility of the polyacene, even an increase in some instances MERCK PATENT GMBH (DE) 2011-05-03 US disclosed
US-7935960-B2 organic field effect transistors; introducing asymmetry into the polyacene derivative affects its solid-state order; combining with organic binder resin results in little or no reduction in charge mobility of the polyacene, even an increase in some instances MERCK PATENT GMBH (DE) 2011-05-03 US disclosed
US-20100308304-A1 ELECTRONIC SHORT CHANNEL DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR FORMULATION MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-12-09 US disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
US-20080191199-A1 Polyacene and Semiconductor Formulation FLEXENABLE TECHNOLOGY LIMITED (GB) 2008-08-14 US disclosed
US-20080191199-A1 Polyacene and Semiconductor Formulation FLEXENABLE TECHNOLOGY LIMITED (GB) 2008-08-14 US disclosed
US-20080142793-A1 Organic Semiconductors UNITED STATES AIR FORCE 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080191199-A1 Polyacene and Semiconductor Formulation OR51E2, PIEZO1, FDFT1 DYRK1A 2867/4885
US-20080142793-A1 Organic Semiconductors ACE, ACE2, TTN DYRK1A 1462/4885
US-20090299070-A1 Organic Semiconductors and Their Manufacture YBX1, CDYL, PROX1 DYRK1A 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.