SCHEMBL458455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL420159	0.81	SERPINE1 (0.71)	SERPINE1CNR1PPARDNR1H4HCAR2
	SCHEMBL418577	0.79	SERPINE1 (0.73)	SERPINE1CNR1AKR1C4AKR1C3AKR1C2
	SCHEMBL458450	0.78	SERPINE1 (0.56)	SERPINE1CNR1FABP3FABP4MPO
	SCHEMBL460371	0.77	SERPINE1 (0.61)	SERPINE1CNR1FABP3FABP4MPO
	SCHEMBL1015517	0.77	SERPINE1 (1.00)	SERPINE1CNR1FABP3FABP4AKR1C4
	SCHEMBL1014985	0.75	SERPINE1 (1.00)	SERPINE1CNR1HCAR2KDM4EPOLB
	SCHEMBL420979	0.73	SERPINE1 (1.00)	SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1
	SCHEMBL419000	0.73	SERPINE1 (0.60)	SERPINE1CNR1PPARDNR1H4HCAR2
	SCHEMBL1012706	0.73	SERPINE1 (0.80)	SERPINE1CNR1FABP3FABP4MPO
	SCHEMBL29838682	0.73	SERPINE1 (1.00)	SERPINE1POLBG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.