Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584693 | 1.00 | ADRB3 (0.50) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL4583995 | 0.91 | ADRB3 (0.57) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL4584000 | 0.91 | ADRB3 (0.57) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL4584705 | 0.86 | ADRB3 (0.60) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL4584696 | 0.86 | ADRB3 (0.60) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| SCHEMBL3194388 | 0.80 | ADRB3 (0.42) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| SCHEMBL3194378 | 0.80 | ADRB3 (0.42) | ADRB3ADRB1ADRB2LMNAHIF1A | |
| SCHEMBL4582748 | 0.80 | MAPT (0.42) | ADRB3ADRB1CYP2D6 | |
| SCHEMBL3026717 | 0.78 | ADRB3 (0.60) | ADRB3ADRB1 | |
| SCHEMBL3026723 | 0.78 | ADRB3 (0.60) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20050137236-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137236-A1 | Aminoalcohol derivatives | GPR39, PRMT9, CHRM2 | ADRB3 86/4885ADRB1 70/4885ADRB2 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.