Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.82 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.82 |
| ▸ | HTR2C | P28335 | 7/20 | 0.82 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583464 | 0.93 | MTNR1A (0.88) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL4584035 | 0.92 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL3831576 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3831492 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3834460 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL4582982 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL5119478 | 0.88 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL5125205 | 0.88 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL4582596 | 0.88 | MTNR1A (0.84) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL4584291 | 0.88 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900723-A1 | New naphthalene derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2008-03-19 | — | — | EP | disclosed |
| US-20080004348-A1 | Naphthalene compounds | LES LABORATOIRES SERVIER (FR) | 2008-01-03 | — | — | US | disclosed |
| WO-2008000969-A1 | NOVEL NAPHTHALENIC DERIVATIVES, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004348-A1 | Naphthalene compounds | MTNR1A, MTNR1B, CNR1 | MTNR1A 1/4885MTNR1B 2/4885HTR2C 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.