Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.60 |
| ▸ | RAF1 | P04049 | 3/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025352 | 1.00 | CSNK1A1 (0.60) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL4028406 | 0.90 | MAPK14 (0.59) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL8551836 | 0.88 | CSNK1A1 (0.46) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL8638666 | 0.88 | CSNK1A1 (0.61) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL4033802 | 0.87 | CSNK1A1 (0.58) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL4025214 | 0.86 | CSNK1A1 (0.67) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL4025331 | 0.86 | CSNK1A1 (0.67) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL4026671 | 0.85 | MAPK11 (0.68) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK11 | |
| SCHEMBL3099823 | 0.84 | HTT (0.59) | GPR119HPGDS | |
| SCHEMBL27538196 | 0.84 | MAPK14 (0.47) | CSNK1A1CSNK1DRPS6KA3MAPK14GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539121-A4 | METHODS OF PROMOTING OSTEOGENESIS | SCIOS INC (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1545535-A4 | TREATMENT OF PAIN BY INHIBITION OF P38 MAP KINASE | SCIOS INC (US) | 2008-06-04 | — | — | EP | disclosed |
| EP-1583535-A4 | METHODS FOR TREATING DIABETES | SCIOS INC (US) | 2008-03-19 | — | — | EP | disclosed |
| EP-1583535-A2 | METHODS FOR TREATING DIABETES | SCIOS INC. (US) | 2005-10-12 | — | — | EP | disclosed |
| EP-1545535-A2 | TREATMENT OF PAIN BY INHIBITION OF P38 MAP KINASE | SCIOS INC. (US) | 2005-06-29 | — | — | EP | disclosed |
| EP-1539121-A2 | METHODS OF PROMOTING OSTEOGENESIS | SCIOS INC. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005032551-A1 | TREATMENT OF CARDIOVASCULAR DISEASE WITH INHIBITORS OF p38 KINASE | SCIOS INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| WO-2004019873-A9 | METHODS OF PROMOTING OSTEOGENESIS | SCIOS INC (US) | 2004-06-24 | — | — | WO | disclosed |
| WO-2004053107-A2 | METHODS FOR TREATING DIABETES | SCIOS INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| WO-2004021988-A2 | TREATMENT OF PAIN BY INHIBITION OF P38 MAP KINASE | SCIOS INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004019873-A2 | METHODS OF PROMOTING OSTEOGENESIS | SCIOS INC. (US) | 2004-03-11 | — | — | WO | disclosed |