Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.45 |
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025352 | 0.88 | CSNK1A1 (0.60) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL4584849 | 0.88 | CSNK1A1 (0.60) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL8549534 | 0.82 | MAPK14 (0.50) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL8554729 | 0.80 | MAPK13 (0.43) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL4721168 | 0.79 | HPGDS (0.43) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL4028406 | 0.78 | MAPK14 (0.59) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL3099823 | 0.78 | HTT (0.59) | HPGDSGPR119 | |
| SCHEMBL6880496 | 0.78 | MAPK14 (0.54) | CSNK1A1CSNK1DMAPK14MAPK13MAPK12 | |
| SCHEMBL4025591 | 0.77 | HTT (0.47) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL8638666 | 0.76 | CSNK1A1 (0.61) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831830-A4 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0831830-A1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040143-A1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |