SCHEMBL458492

SCHEMBL458492

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COCl

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2889691 1.00 MPI (0.39) MPI
SCHEMBL9495338 0.93 MPI (0.41) MPI
SCHEMBL9496695 0.93 MPI (0.41) MPI
SCHEMBL565806 0.78 MPI (0.39) MPI
SCHEMBL459484 0.78 MPI (0.39) MPI
SCHEMBL1763816 0.78 MPI (0.39) MPI
SCHEMBL10489052 0.78 MPI (0.39) MPI
SCHEMBL1586372 0.78 MPI (0.39) MPI
SCHEMBL4160815 0.78 MPI (0.39) MPI
SCHEMBL5453964 0.78 MPI (0.39) MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120094946-A1 GLYCOSYLATED CHLORAMBUCIL ANALOGS AND USES THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-04-19 US claimed
EP-4438734-A2 REPROGRAMMING OF CELLS TO A NEW FATE The Scripps Research Institute (US) 2024-10-02 EP disclosed
EP-3399026-B1 REPROGRAMMING OF CELLS TO A NEW FATE SCRIPPS RESEARCH INST (US) 2024-06-26 EP disclosed
US-20210189348-A1 REPROGRAMMING OF CELLS TO A NEW FATE THE SCRIPPS RESEARCH INSTITUTE 2021-06-24 US disclosed
US-10934528-B2 Reprogramming of cells to a new fate THE SCRIPPS RESEARCH INSTITUTE (US) 2021-03-02 US disclosed
US-10308912-B2 Reprogramming of cells to a new fate THE SCRIPPS RESEARCH INSTITUTE (US) 2019-06-04 US disclosed
EP-3399026-A1 REPROGRAMMING OF CELLS TO A NEW FATE The Scripps Research Institute (US) 2018-11-07 EP disclosed
EP-2580320-B1 REPROGRAMMING OF CELLS TO A NEW FATE SCRIPPS RESEARCH INST (US) 2018-08-01 EP disclosed
US-20170159019-A1 REPROGRAMMING OF CELLS TO A NEW FATE THE SCRIPPS RESEARCH INSTITUTE 2017-06-08 US disclosed
US-9556417-B2 Reprogramming of cells to a new fate THE SCRIPPS RESEARCH INSTITUTE (US) 2017-01-31 US disclosed
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis INTERSTITIAL THERAPEUTICS (CH) 2009-12-31 US disclosed
EP-1789107-B1 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2009-05-27 EP disclosed
US-20070292478-A1 Medical Implant Provided with Inhibitors of Atp Synthesis INTERSTITIAL THERAPEUTICS (CH) 2007-12-20 US disclosed
EP-1789030-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP disclosed
EP-1789107-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP disclosed
WO-2006024488-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO disclosed
WO-2006024492-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO disclosed
US-4442123-A 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1984-04-10 US disclosed
EP-0015652-B1 6-CHLORO-6-DEOXY-D-HEXITOLS, THEIR ESTERS, THEIR PREPARATION, FERTILITY CONTROL COMPOSITIONS CONTAINING THEM AND THEIR USE IN A CONTRACEPTIVE METHOD TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1983-01-19 EP disclosed
EP-0015652-A1 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis ATP5ME, ATP5F1A, ATP5MG MPI 193/4885
US-20120094946-A1 GLYCOSYLATED CHLORAMBUCIL ANALOGS AND USES THEREOF CD22, UGGT1, UGCG MPI 193/4885
US-20070292478-A1 Medical Implant Provided with Inhibitors of Atp Synthesis ATP5F1A, ATP5ME, ATP5MG MPI 365/4885
US-10934528-B2 Reprogramming of cells to a new fate ALPG, POU5F1, POU2F1 MPI 1112/4885
US-20170159019-A1 REPROGRAMMING OF CELLS TO A NEW FATE ALPG, POU5F1, POU2F1 MPI 1112/4885
US-20210189348-A1 REPROGRAMMING OF CELLS TO A NEW FATE ALPG, POU5F1, POU2F1 MPI 1112/4885
US-10308912-B2 Reprogramming of cells to a new fate ALPG, POU5F1, POU2F1 MPI 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.