Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232676 | 0.90 | CA12 (0.51) | KEAP1CA12CA14CA2MMP2 | |
| SCHEMBL3725975 | 0.90 | CA12 (0.51) | KEAP1CA12CA14CA2MMP2 | |
| Hydrochloric Acid SCHEMBL27787241 | 0.88 | CA12 (0.50) | KEAP1CA12CA14CA2MMP2 | |
| SCHEMBL2524191 | 0.80 | CYP2D6 (0.38) | KEAP1CA12CA14CA2MMP2 | |
| SCHEMBL18260692 | 0.79 | TTR (0.51) | CYP1A2 | |
| Sulfuric Acid SCHEMBL27899530 | 0.78 | KDM4E (0.56) | KEAP1CA12CA14CA2MMP2 | |
| Sulfuric Acid SCHEMBL6255048 | 0.76 | ANPEP (0.46) | KEAP1CA12CA14CA2MMP2 | |
| SCHEMBL28700566 | 0.75 | KEAP1 (0.67) | KEAP1CA12CA14CA2MMP2 | |
| SCHEMBL11336488 | 0.75 | CA12 (0.56) | KEAP1CA12CA14CA2MMP2 | |
| SCHEMBL3250893 | 0.75 | KDM4E (0.59) | KEAP1CA12CA14CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802756-A4 | PROBE OF HUMAN PAPILLOMAVIRUS AND DNA CHIP COMPRISING THE SAME | GOODGENE INC (KR) | 2008-04-09 | — | — | EP | claimed |
| EP-1802756-A1 | PROBE OF HUMAN PAPILLOMAVIRUS AND DNA CHIP COMPRISING THE SAME | Goodgene Inc. (KR) | 2007-07-04 | — | — | EP | claimed |
| WO-2006038753-A1 | PROBE OF HUMAN PAPILLOMAVIRUS AND DNA CHIP COMPRISING THE SAME | GOODGENE INC. (KR) | 2006-04-13 | — | — | WO | claimed |