Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534204 | 0.81 | CDK2 (0.44) | — | |
| SCHEMBL13500404 | 0.81 | MAPK14 (0.40) | POLBNPSR1CNR2RAB9AKDM4E | |
| SCHEMBL4573490 | 0.79 | MCHR1 (0.48) | CNR2IRAK4FFAR2CNR1 | |
| SCHEMBL3617502 | 0.79 | TSHR (0.44) | CNR2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3615790 | 0.78 | GRIN2B (0.41) | POLBNPSR1IRAK4FFAR2RAB9A | |
| SCHEMBL3606838 | 0.78 | CTSD (0.41) | NPSR1CNR2IRAK4NPC1RAB9A | |
| SCHEMBL3605500 | 0.78 | FFAR2 (0.37) | POLBNPSR1CNR2FFAR2NPC1 | |
| SCHEMBL3609937 | 0.76 | ACACB (0.43) | CNR2IRAK4NPC1RAB9AKDM4E | |
| SCHEMBL3335280 | 0.76 | RXFP1 (0.43) | POLBNPSR1IRAK4ALDH1A1 | |
| SCHEMBL3600185 | 0.75 | FFAR2 (0.40) | POLBNPSR1IRAK4FFAR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077650-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |