Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21854489 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL29174628 | 0.83 | MAPT (0.48) | ALDH1A1SMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL30725465 | 0.83 | MAPT (0.48) | ALDH1A1SMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL460319 | 0.82 | HTT (0.48) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL4184662 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL15109519 | 0.80 | MAPT (0.37) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL26802625 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL16481703 | 0.76 | TNF (0.35) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL31493047 | 0.76 | MAPT (0.39) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL16449235 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |