Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | TP53 | P04637 | 7/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174628 | 1.00 | MAPT (0.48) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL21854489 | 0.87 | ALDH1A1 (0.38) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL15109519 | 0.84 | MAPT (0.37) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL4184662 | 0.84 | ALDH1A1 (0.41) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL458516 | 0.83 | ALDH1A1 (0.41) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL16709919 | 0.80 | MAPT (0.67) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL30173602 | 0.80 | MAPT (0.67) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL16449235 | 0.77 | ALDH1A1 (0.40) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL690399 | 0.75 | DGAT1 (0.46) | MAPTTP53TLR9NPC1ALDH1A1 | |
| SCHEMBL30937640 | 0.73 | ALDH1A1 (0.38) | MAPTTP53TLR9NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |